Donato Iacovazzo

Donato Iacovazzo2018-10-16T09:47:10+00:00

Department of Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK



Date of birth:       19th Feb 1985
Place of birth:      Grottaglie (Taranto, Italy)
Work address:     Department of Endocrinology,
William Harvey Research Institute, Barts and the London School of Medicine,
Queen Mary University of London, London EC1M 6BQ
Tel: +44 20 7882 6204, email:



May 2015            CCT in Endocrinology (UCSC, Rome, Italy)
October 2009      M.D. Summa Cum Laude (UCSC, Rome, Italy)
August 2008        Visiting student (Johns Hopkins University, Baltimore, MD)



2015-today         Clinical Research Fellow – Department of Endocrinology, Barts and The London
2010-2015           Specialty Training in Endocrinology (Policlinico “A. Gemelli”, Rome, Italy)    



Sir George Alberti Research Training Fellowship funded by Diabetes UK – 2016-2019
Featured clinical case prize – SfE BES Conference 2017
Highly commended oral communication – SfE BES Conference 2016
AMEND Young Investigator’s award – SfE BES Conference 2016
Outstanding abstract award – Endocrine Society’s 98th Annual Meeting 2016
Award for poster presentation – National Cases SfE Meeting 2016
Early career travel grant – Endocrine Society’s 97th Annual Meeting 2015
Travel grant – 13th International Pituitary Congress 2013



– Iacovazzo D, Flanagan SE, Walker E, Quezado R, et al. (2018) MAFA missense mutation causes familial insulinomatosis and diabetes mellitus. Proc Natl Acad Sci USA 115(5):1027-1032.
– Salvatori R, Radian S, Diekmann Y, Iacovazzo D, et al. (2017) In-frame seven amino-acid duplication in AIP arose over the last 3000 years, disrupts protein interaction and stability and is associated with gigantism. Eur J Endocrinol 177(3):257-266.
– Kiefer FW, et al. (2017) PRKAR1A mutation causing pituitary-dependent Cushing disease in a patient with Carney complex. Eur J Endocrinol 177(2):K7-K12.
– Rodd C, et al. (2016) Somatic GPR101 Duplication Causing X-Linked Acrogigantism (XLAG)-Diagnosis and Management. J Clin Endocrinol Metab 101(5):1927-1930.
– Iacovazzo D & Korbonits M (2016) Gigantism: X-linked acrogigantism and GPR101 mutations. Growth Horm IGF Res 30-31:64-69.
– Iacovazzo D, et al. (2016) Germline or somatic GPR101 duplication leads to X-linked acrogigantism: a clinico-pathological and genetic study. Acta Neuropathol Commun 4(1):56.
– Iacovazzo D, et al. (2016) Factors predicting pasireotide responsiveness in somatotroph pituitary adenomas resistant to first-generation somatostatin analogues: an immunohistochemical study. Eur J Endocrinol 174(2):241-250.
– Hernandez-Ramirez LC, et al. (2016) Rapid Proteasomal Degradation of Mutant Proteins Is the Primary Mechanism Leading to Tumorigenesis in Patients With Missense AIP Mutations. J Clin Endocrinol Metab 101(8):3144-3154.
– Hernandez-Ramirez LC, et al. (2015) Landscape of Familial Isolated and Young-Onset Pituitary Adenomas: Prospective Diagnosis in AIP Mutation Carriers. J Clin Endocrinol Metab 100(9):E1242-1254.